Cellular damage: Causes of cellular damage. Mechanisms of cell damage. Cell adaptation. Reversible and irreversible damage. Necrosis. Apoptosis.
Aging.
Acute inflammation: Definition and causes of acute inflammation. Stages of acute inflammation. The cells of acute inflammation. The chemical mediators of inflammation. Types of acute inflammation and of exudate.
Chronic inflammation: Classification, causes and types of chronic inflammation. Cells of chronic inflammation. Typical lesions of chronic inflammation. Granulomas.
Systemic phenomena associated with inflammation.
Renewal, regeneration and tissue repair.
Neoplasia: natural history, benign and malignant tumors, diagnosis, classification, staging, oncogenes, tumor suppressors, cell cycle, inheritance and tumors, angiogenesis, invasion and metastasis, chemical and physical carcinogenesis. Neoplastic stem cells. Immunity and tumors.
Adapted physical activity and cancer: Role of physical activity in primary, secondary and tertiary prevention of tumors, mechanisms of action of physical activity in oncology, physical activity and more frequent human tumors, limitations of physical activity in oncology.
Pathology of lymphoid and hematopoietic tissues: Pathophysiology of the haematopoietic system. Classification, genetics, etiology and pathogenesis of anemia. Anemias in the sportsman. Myeloproliferative syndromes. Acute and chronic leukemias. Lymphomas. Multiple myeloma.
Pathophysiology of haemostasis. Plateletopathy and platelet diseases.
Diabetes mellitus: classification, glucose homeostasis, pathogenesis of type 1 and 2 diabetes, monogenic forms of diabetes, gestational diabetes, pathogenesis of diabetes complications.