Basic knowledge of Biochemistry, Molecular Biology and Microbiology.
Introduction to genetics (1 h).
Cellular cycle, mitosis and meiosis (2 h).
Mendelian genetics (4 h).
Extensions of Mendelism (3 h).
Chromosomal basis of Mendelism (2 h).
Cytogenetics (3 h).
Linkage, crossing-over and chromosome mapping (4 h).
Construction of genetic maps (2 h).
Genetics of bacteria and viruses (2 h).
DNA and chromosome structure (2 h).
DNA replication (2 h).
Recombinant DNA techniques (2 h).
Cloning vectors (2 h).
Recombinant DNA libraries (2 h).
Genetic polymorphism (2 h).
Sequencing of the human genome (2 h).
The genetic code (1 h).
Gene mutations (1 h).
Cause of mutations (1 h).
Regulation of gene expression (3 h).
Genetics of cancer (2 h).
Population genetics (3 h).
Snustad, Simmons - Principles of Genetics (6th ed) - 2012 - ed. John Wiley & Sons.
Lecture slides are available on the course website http://e-scienzeetecnologie.uniparthenope.it/course/view.php?id=192
The exam (oral) will focus on the resolution of some exercises (Mendel's laws, modification of Mendelian ratios, Chi-square test and Three-point crosses to calculate the map distances) and on the discussion concerning topics listed in the syllabus.
Traditional lectures integrated with exercises in class.